- Physics models for the interaction of charged particles with biological molecules in the condensed-phase.
- Calculations of inelastic cross sections and stopping-power from first-principles using the dielectric theory.
- Monte-Carlo radiation transport simulations using track-structure and condensed-history methods.
- Microdosimetry of radiation quality (RBE, QF) with application to radiation protection (including space radiation protection) and radiotherapy.
- Dosimetry of targeted radionuclide therapy with β- and Auger-emitters at the (sub) cellular level.
- Monte-Carlo modeling of radiation-induced DNA damage.
- Dosimetric characteristics of therapeutic hadron-beams.
- Extension of the GEANT4-DNA code to Medical Physics applications.