- Development of physics models for charged-particle interactions with matter to be used for Monte Carlo radiation transport simulations.
- Application of track-structure (or event-by-event) and condensed-history Monte Carlo techniques to microdosimetry (radiation quality problems), targeted radionuclide therapy (dosimetry of β- and Auger-emitters at the cellular level), ion-beam radiotherapy (Bragg peak characteristics), nanoparticle-enhanced radiotherapy, and radiation biophysics (DNA damage and cell survival predictions).
- Extension and development of the EM physics models of the GEANT4-DNA code (CERN/CNRS) and applications to various problems in Medical Physics.